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PRORSD1P (Prolyl-tRNA synthetase associated domain containing 1, pseudogene) is a human gene classified as a pseudogene, located on chromosome 2[12][13]. Pseudogenes are DNA sequences similar to known genes but typically lack the ability to code for functional proteins. While some predictions have suggested this gene could enable aminoacyl-tRNA editing activity and may be involved in aminoacyl-tRNA metabolism related to translational fidelity, these functions are not confirmed in humans for this pseudogene[1][11]. There is no evidence of this gene being functionally relevant, nor is it recognized as a therapeutic target, biomarker, or safety concern in clinical practice. Multiple aliases exist, sometimes reflecting its evolutionary history or functional annotation in non-human species, but in humans, PRORSD1P remains a non-functional remnant of a protein-coding ancestor[1][11][13].
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