Proteasome 26S subunit, ATPase 2 pseudogene 2 (PSMC2P2)

PSMC2 pseudogene 2 (PSMC2P2) is a non-protein-coding pseudogene derived from the functional gene encoding Proteasome 26S subunit, ATPase 2 (PSMC2)[4]. Pseudogenes like PSMC2P2 do not produce functional proteins, and there is no evidence that PSMC2P2 has any biological or pathological roles, nor is it a therapeutic target. In contrast, the parent gene PSMC2 encodes an essential ATPase subunit of the 26S proteasome with established roles in protein degradation, cell cycle regulation, and oncogenesis[1][2][3]. However, these functions do not apply to the pseudogene. \nKey notes: \n- The term \"PSMC2 pseudogene 2\" refers specifically to a nonfunctional, likely non-expressed genomic locus and not to an active protein or actionable therapeutic target. \n- Information found for the active gene (PSMC2) should not be attributed to this pseudogene. \n- Pseudogenes are generally ignored in drug targeting and clinical contexts unless shown to exert regulatory functions, which is not the case here.

Other names

PSMC2 pseudogene 2proteasome (prosome, macropain) 26S subunit, ATPase, 2 pseudogeneproteasome 26S subunit, ATPase 2 pseudogenePSMC2P2