Proteasome 26S subunit, ATPase 3 pseudogene 1 (PSMC3P1)

PSMC3P1 (Proteasome 26S subunit, ATPase 3 pseudogene 1) is a **pseudogene**, not a protein-coding gene[1]. It is related by sequence to the protein-coding gene PSMC3, which encodes a crucial component of the 26S proteasome complex—a major protein degradation machine in eukaryotic cells[1][3][5]. However, **PSMC3P1 does not encode a functional protein** and lacks evidence for direct biological functions, involvement in diseases, or roles as a therapeutic target. Pseudogenes like PSMC3P1 may have regulatory or evolutionary significance but are not considered drug targets or involved in classic protein-mediated pathways[1]. **Key context:** - PSMC3P1 is a *non-coding pseudogene* and should not be confused with the protein-coding gene **PSMC3** (Proteasome 26S subunit, ATPase 3 / also known as 26S protease regulatory subunit 6A)[1][3][5]. - There is **no evidence or literature supporting PSMC3P1 as a therapeutic target, biomarker, or drug-interactive entity**[1]. - Molecular function, disease association, biomarkers, interacting drugs, and safety concerns are not applicable to pseudogenes without known function[1]. - **If the intention was to inquire about the protein-coding gene PSMC3, refer instead to "Proteasome 26S subunit, ATPase 3" (PSMC3)[3][5].** Sources: - [1] GeneCards: PSMC3P1 – Pseudogene information - [3][5] GeneCards/Wikipedia: PSMC3 – Protein-coding counterpart with detailed molecular function **Summary:** PSMC3P1 is a pseudogene, not a functional protein or therapeutic target; information about biologically relevant roles, pathways, or druggability should refer to its protein-coding counterpart, PSMC3, not this pseudogene[1].

Other names

PSMC3Pproteasome (prosome, macropain) 26S subunit, ATPase, 3 pseudogenePSMC3P1