Target intelligence / Profile preview

Protein transport between endoplasmic reticulum and Golgi apparatus (COP-I mediated) (None)

Target: None
Molecular classification: Protein Complex, Coat Protein Complex, COPI

Overview

COPI-mediated transport refers to the process by which proteins and lipids are shuttled between the endoplasmic reticulum (ER) and the Golgi apparatus, as well as within Golgi compartments. COPI (Coat Protein Complex I) is a multi-subunit protein complex that forms a coat around vesicles responsible for this trafficking. The primary function of COPI is retrograde transport—moving materials from the cis-Golgi back to the ER—and also facilitating intra-Golgi transport.

Mechanism of action

N/A

Biological functions

Retrograde Transport (cis-Golgi to ER)Intra-Golgi TraffickingCargo RecognitionStructural Maintenance of Golgi

Disease associations

Defects in protein processing/secretionOrganelle morphology defects

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