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ENSG00000227163 is a pseudogene similar in sequence to the ATP5G1 gene, which encodes the c subunit of the mitochondrial F0 ATP synthase complex responsible for proton translocation as part of ATP synthesis in mitochondria. As a pseudogene, ENSG00000227163 does not encode a functional protein and has no direct biological or therapeutic relevance. It is not considered a molecular target in drug discovery or clinical practice. Key distinctions: - Pseudogenes share sequence similarity with functional genes but are generally non-functional due to mutations or lack of transcription. - ATP5G1 encodes a crucial part of the ATP synthase machinery, whereas ENSG00000227163 only shares similarity and no functional role. - There are no recorded disease associations, biological functions, or interacting drugs specific to this pseudogene. If you require information on the functional ATP synthase subunit c (ATP5G1), which is a vital enzyme component, please specify, as it differs significantly from this pseudogene.
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