Pseudogene similar to part of phospholipase C, gamma 1

ENSG00000226338 is a pseudogene annotated as "pseudogene similar to part of phospholipase C, gamma 1 (PLCG1)"[1][5]. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they arise by gene duplication or retrotransposition and typically acquire disabling mutations[2][4]. This entry is not an active protein-coding gene, nor is there evidence it encodes a functional protein or acts as a therapeutic target. While some pseudogenes may have regulatory roles, there is no evidence for such a function here. Since this entry lacks a functional gene product, molecular function, or established disease association, it is inappropriate to consider it a therapeutic target or druggable entity[1][5][2]. Note: This pseudogene is not the functional phospholipase C, gamma 1 protein (PLCG1, ENSG00000124181) but merely shares sequence similarity[1][3][7].

Other names

ENSG00000226338Pseudogene similar to part of PLCG1