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This gene, designated ENSG00000225384, is a human pseudogene annotated as "pseudogene similar to part of poly(A) polymerase alpha (PAPOLA)." Pseudogenes are segments of DNA that resemble functional genes but typically do not encode active proteins due to disabling mutations or lack of regulatory features[1][3][7]. This particular pseudogene is related by sequence to the PAPOLA gene, which encodes poly(A) polymerase alpha, an enzyme involved in mRNA processing; however, there is no evidence that this pseudogene produces a functional protein or is involved in physiological or disease-related processes in humans[1][3][7]. Therefore, it lacks the key properties that define druggable therapeutic targets or meaningful molecular functions.
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