Pseudogene similar to part of SMT3 suppressor of mif two 3 (yeast)

This genomic locus is a **pseudogene** with no known protein-coding function, annotated as similar to part of SMT3 suppressor of mif two 3 (yeast). SMT3 suppressor of mif two 3 is a yeast gene related to the human SUMO (Small Ubiquitin-like Modifier) gene family. However, ENSG00000235190 itself does not encode a functional SUMO protein, nor does it participate in sumoylation or related cellular processes. Key context and supporting details: - The annotation as a "pseudogene similar to part of SMT3 suppressor of mif two 3" means it derives from sequence homology to a segment of a yeast gene (SMT3), but lacks protein-coding and functional elements. - There are multiple functional SUMO family members (such as SUMO2, SUMO3) in humans, which are involved in post-translational modification, but this pseudogene has no documented role and is not referenced as a target in biomedical literature. - GeneCards, HUGO Gene Nomenclature Committee, and related databases classify ENSG00000235190 specifically as a pseudogene—the most authoritative designation in genomic research. - It is not a member of any canonical therapeutic target families. Human protein-coding SUMO genes have aliases and defined molecular roles, which do not extend to this pseudogene. In summary, **ENSG00000235190 is not a drug target and is instead classified as a non-functional pseudogene with a nomenclature reflecting homology to the yeast SMT3 gene. All other fields related to therapeutic targeting, biological function, and druggability are not applicable**.

Other names

SMT3 suppressor of mif two 3-related pseudogene