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Pseudogene similar to part of vitamin K epoxide reductase complex, subunit 1-like 1 (ENSG00000239985)

Target
ENSG00000239985
Molecular classification
Other (Pseudogene)
01

Overview

ENSG00000239985 encodes a pseudogene that is similar in sequence to the protein-coding gene VKORC1L1 (Vitamin K epoxide reductase complex, subunit 1-like 1). VKORC1L1 itself is an enzyme involved in the vitamin K cycle and is important for the carboxylation of glutamate residues on vitamin K-dependent proteins[2][3]. However, this pseudogene does not encode a functional protein and does not have a role in vitamin K metabolism or as a drug target. Pseudogenes are generally considered evolutionary remnants and have no direct physiological or therapeutic function.\n\nNote: If you intended the functional target VKORC1L1, the canonical Ensembl gene is ENSG00000196715, and it *is* a functional enzyme involved in vitamin K-dependent processes[2][3]. The provided ENSG00000239985 correctly refers to a pseudogene, making it an inappropriate choice as a pharmacological target.\n\nFor information on the active VKORC1L1 gene/protein, see canonical references for "Vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1)", which is a protein-coding enzyme and a functional family member with actual biological roles[2][3].

02

Mechanism of action

None applicable.

03

Biological functions

None (pseudogenes do not produce functional proteins and generally do not have direct biological functions)
04

Disease associations

Other (Pseudogenes are rarely implicated in disease, except in unusual cases such as pseudogene-derived regulatory RNAs, which is not described for this target.)
05

Safety considerations

None specific (pseudogenes are not considered therapeutic targets and are not associated with safety concerns).

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