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Pseudogene similar to the likely ortholog of mouse gene rich cluster, C10 (ENSG00000228289)

Target
ENSG00000228289
Molecular classification
Pseudogene, Long non-coding RNA (lncRNA), Other
01

Overview

ENSG00000228289 is annotated as a **pseudogene**, defined as a DNA sequence with high homology to a functional gene but unable to code for a functional protein product[1][2]. Most pseudogenes do not have a direct biological function, though some are transcribed into RNA and may participate in regulatory networks through RNA interference mechanisms or as miRNA sponges[3][4]. There are no known therapeutic, pharmacologic, or classical molecular target roles for this entity—pseudogenes are typically not directly targeted in drug development. This specific pseudogene appears to be annotated based on sequence similarity to a gene in the mouse genome but lacks evidence of protein-coding capacity or therapeutic relevance. In summary, **ENSG00000228289** is not a protein, enzyme, receptor, or classical molecular target suitable for therapeutic intervention, and there is nothing to suggest it functions as one. Its only established role is as a **pseudogene**, possibly transcribed as non-coding RNA without evidence of direct clinical utility[1][2][3].

02

Biological functions

Other (most pseudogenes are nonfunctional, though some may have gene regulatory functions such as acting as competing endogenous RNAs or producing regulatory RNAs[3][4])
03

Disease associations

Other (pseudogenes may have roles in gene regulation and have been implicated in cancer and other diseases, though such functions are rare and gene-specific[3])

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