Pseudouridine 5'-phosphatase pseudogene 1 (PUDPP1)

Pseudouridine 5'-phosphatase pseudogene 1 (PUDPP1) is classified as a pseudogene, meaning it resembles a protein-coding gene but is generally not transcribed or translated into a functional protein[1]. As a pseudogene, it does not act as a therapeutic target, nor does it have any established role in disease, biological function, or pharmacology[1]. Multiple aliases have arisen from its sequence similarity to other hydrolase domain-containing genes, but these refer to non-functional (pseudogene) copies[1]. Note: - There is a functional paralog, Pseudouridine 5'-phosphatase (PUDP/HDHD1A), which is an enzyme that dephosphorylates pseudouridine 5'-phosphate during RNA metabolism[3][5][7]. However, PUDPP1 is specifically non-functional and not equivalent to PUDP/HDHD1A. - If seeking a true protein-coding target with related activity (pseudouridine metabolism), see Pseudouridine 5'-phosphatase (PUDP, HDHD1A) rather than PUDPP1[3][5][7]. This target is therefore not a valid drug target and is a pseudogene, not an enzyme, receptor, or other actionable protein.

Other names

Haloacid dehalogenase-like hydrolase domain containing 1 pseudogene 1Family with sequence similarity 16, member A, Y-linkedHDHD family member 1B, pseudogeneFAM16AYHDHD1BPHDHD1P1Haloacid dehalogenase-like hydrolase domain containing 1A pseudogene

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