PTGES2 antisense RNA 1 (head to head) (PTGES2-AS1)

PTGES2 divergent transcript (PTGES2-DT, also known as PTGES2-AS1 or PTGES2 antisense RNA 1) is a long non-coding RNA (lncRNA) gene located at the PTGES2 genomic locus, transcribed in the opposite direction ("head-to-head" antisense) relative to the PTGES2 gene. Unlike PTGES2, which encodes a membrane-associated enzyme involved in prostaglandin E2 synthesis, PTGES2-DT does not code for a protein. Its specific biological function, clinical significance, and disease associations remain uncharacterized, and there are no known drugs or therapeutics targeting this non-coding RNA. This transcript should not be confused with the protein-coding PTGES2 or with small-molecule drug targets[7]. If you are seeking information on the prostaglandin E synthase 2 enzyme (PTGES2, a therapeutic target in inflammation and cancer), please refer to its associated entries, as PTGES2-DT is a distinct, non-coding RNA with no current evidence of therapeutic relevance or established biological function[2][7].

Other names

PTGES2-DTPTGES2 divergent transcriptPTGES2-AS1