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This target group includes multiple classes of regulatory biomolecules crucial for orchestrating cellular communication during tissue repair/regeneration as well as maintaining homeostasis within tissues such as skin and nervous system. Their interplay determines outcomes ranging from effective wound closure to persistent non-healing ulcers depending on local balance between stimulatory signals from growth factors/cytokines/neurotrophins versus inhibitory control via protease inhibitors within an appropriate extracellular matrix context.
Varies depending on the specific molecule. Examples include: Growth factor receptor activation, cytokine receptor modulation, protease inhibition, ECM scaffolding, neurotrophic receptor activation.
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