Reverse Transcriptase (Viral) (RT)

Reverse transcriptase (RT) is an enzyme found in retroviruses and some other viruses, such as HIV and hepatitis B virus. Its primary function is to convert the viral RNA genome into complementary DNA (cDNA), a process known as reverse transcription. This cDNA can then integrate into the host cell's genome, allowing the virus to hijack the host's replication machinery for its own propagation. RT catalyzes RNA-dependent DNA polymerase, Ribonuclease H (RNase H), and DNA-dependent DNA polymerase activities. RTs are major targets for antiviral drugs used in treating infections like HIV/AIDS.

Inhibition of reverse transcriptase activity, preventing viral cDNA synthesis