RNA, 5.8S ribosomal pseudogene 7 (RNA5-8SP7)

RNA, 5.8S ribosomal pseudogene 7 (RNA5-8SP7) is a **pseudogene** located on human chromosome 20 (20p12)[2][4][5][6]. It is a non-functional, processed sequence that resembles the gene encoding 5.8S ribosomal RNA. Unlike functional 5.8S ribosomal RNA genes, which are vital structural components of the large (60S) subunit of the eukaryotic ribosome and play key roles in protein synthesis[1][3], this pseudogene does not produce a functional RNA or protein product. Ribosomal RNA pseudogenes commonly arise through evolutionary processes such as sequence duplication and subsequent loss of function and are often considered genomic "junk DNA"[7]. RNA5-8SP7 has no known or predicted biological activity, does not participate in cellular pathways, and is not known to be involved in disease, biomarker development, or drug targeting. Additional context: - RNA, 5.8S ribosomal pseudogene 7 is annotated in genome databases as a pseudogene, rather than an active ribosomal RNA gene[5][6]. - No evidence supports its role as a therapeutic target, biomarker, or disease gene[2][4][5]. - Pseudogenes of ribosomal RNAs are prevalent throughout the genome, furthering the background sequence diversity and sometimes serving as evolutionary remnants[7].

Other names

RN5-8S7RNA, 5.8S ribosomal 7RNA5-8SP7