RNA, 5S ribosomal pseudogene 114 (RNA5SP114)

RNA, 5S ribosomal pseudogene 114 (RNA5SP114) is a non-functional genomic sequence derived from a 5S ribosomal RNA gene. Pseudogenes like RNA5SP114 typically arise from gene duplication or retrotransposition events that become inactivated by mutations, leading to loss of rRNA coding capacity. While some pseudogenes may be transcribed, they generally do not encode functional RNAs or proteins and are not drug targets. Functional 5S rRNA forms part of the large ribosomal subunit critical for protein translation, but RNA5SP114 is a non-functional variant and does not contribute to ribosome biogenesis or function. Key points: - RNA5SP114 is a pseudogene, not a functional target or therapeutic molecule. - It is related to the 5S ribosomal RNA gene family but is non-functional due to accumulated mutations. - There is no current evidence of direct disease association, druggability, or biomarker utility for this specific pseudogene. - While some pseudogenes have emerging regulatory or biomarker roles in cancer, such roles have not been reported for RNA5SP114.

Other names

RN5S114RNA5SP114RNA, 5S ribosomal 114

None applicable