Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 126 (RNA5SP126)

Target
RNA5SP126
Molecular classification
Pseudogene, Processed pseudogene
01

Overview

RNA, 5S ribosomal pseudogene 126 is a processed pseudogene of the 5S ribosomal RNA gene family and does not encode a functional RNA product[2][6]. Pseudogenes arise from gene duplication or retrotransposition events and typically lack the regulatory elements and intact sequences required for expression and function. Unlike functional 5S rRNA, which is a structural and functional component of the large ribosomal subunit required for protein synthesis in all domains of life[1][3][5], RNA5SP126 does not participate in ribosome assembly or cellular metabolism. Some pseudogenes are transcribed or have regulatory effects, occasionally contributing to disease or acting as non-coding RNAs in cancer[4], but there is no evidence indicating RNA5SP126 has such roles. Its presence is primarily used as a genomic marker, and it is not considered a druggable or therapeutic target.

Other names
RN5S126RNA5SP126RNA, 5S ribosomal 126
02

Disease associations

Other (pseudogenes have been implicated in cancer as biomarkers or regulatory RNAs, but specific disease involvement for RNA5SP126 is not established)

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