RNA, 5S ribosomal pseudogene 145 (RNA5SP145)

RNA, 5S ribosomal pseudogene 145 (RNA5SP145) is a member of the 5S rRNA pseudogene family, typically classified as a processed pseudogene[4]. While 5S rRNA is a 120-nucleotide essential structural RNA incorporated into ribosomes and required for normal protein translation in all cellular life forms except for mitochondrial ribosomes in animals and fungi[1][3], its pseudogenes, such as RNA5SP145, are defective, non-functional genomic sequences that arise from retrotransposition or duplication events but cannot produce a functional 5S rRNA molecule[4]. Processed rRNA pseudogenes like RNA5SP145 are not transcribed or involved in any known cellular mechanisms, have no protein product, and do not play a direct role in cellular biology, disease, or therapy. Key Points: - The correct canonical form is "RNA, 5S ribosomal pseudogene 145". - This is not a therapeutic target, gene, receptor, or enzyme; it is an rRNA pseudogene. - Pseudogenes such as RNA5SP145 may clutter genomic annotation sets but do not contribute to ribosome assembly or function and are not linked to diseases, drug action, or safety concerns[4]. - Its only molecular classification is as an "rRNA pseudogene" under "Other" (non-coding RNA pseudogenes). If you are seeking information on an actual ribosomal target with possible therapeutic significance, such as "5S ribosomal RNA" (not the pseudogene), please specify. 5S rRNA (the functional gene/product) is essential for ribosome structure and protein synthesis, but its pseudogenes, including RNA5SP145, are not functional and have no current clinical relevance[1][3][4].

Other names

RN5S145RNA, 5S ribosomal 145RNA5SP145

None (no known mechanisms of drug action since it is not a therapeutic target)