RNA, 5S ribosomal pseudogene 146 (RNA5SP146)

RNA, 5S ribosomal pseudogene 146 (RNA5SP146) is a processed pseudogene related to the 5S ribosomal RNA gene family. Unlike functional 5S rRNA, which forms an essential part of the large ribosomal subunit and is involved in ribosome assembly and protein synthesis[1][3][5], processed rRNA pseudogenes like RNA5SP146 arise from retrotransposition events that copy RNA back into the genome without introns or regulatory sequences. These pseudogenes do not encode proteins or functional RNA, and typically lack biological activity. Although some pseudogenes can have regulatory roles, most—including RNA5SP146—are presumed non-functional and have no demonstrated relevance as therapeutic targets, disease markers, or drug interaction sites[2][4][6]. If you require data about canonical 5S ribosomal RNA, note that this is a functional ribosomal RNA involved in the structure, assembly, and functional integration of the ribosome's large subunit[1][3][5]. RNA5SP146, however, is not a functional molecule but a genome-embedded pseudogene.

Other names

RN5S146RNA, 5S ribosomal 146RNA, 5S ribosomal pseudogene 146RNA5SP146