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Target intelligence / Profile preview
RNA, 5S ribosomal pseudogene 158 (RNA5SP158)
- Target
- RNA5SP158
- Molecular classification
- Pseudogene, rRNA pseudogene
01
Overview
RNA, 5S ribosomal pseudogene 158 (RNA5SP158) is an annotated human pseudogene related in sequence to the 5S ribosomal RNA (rRNA) gene. The functional 5S rRNA is a highly conserved, approximately 120-nucleotide non-coding RNA component of the large ribosomal subunit critical for ribosome structural integrity and function in protein synthesis. RNA5SP158, however, is a non-coding pseudogene: it does not code for a functional 5S rRNA molecule. While some pseudogenes are occasionally transcribed and a fraction may be translated to short peptides, there is no evidence that RNA5SP158 has any biological or pathological significance, druggability, or is used as a diagnostic biomarker. Its primary significance lies in genomics research as a marker of evolutionary history and gene family expansion rather than as a molecular target.
- Other names
- RN5S158RNA 5S ribosomal pseudogene 158RNA, 5S ribosomal 158RNA5SP158
02
Mechanism of action
Not applicable. Mechanisms only relevant if the gene product is a validated target, which is not the case for a pseudogene
03
Biological functions
None established; pseudogenes generally do not have known biological functions in the canonical, protein-coding senseMay rarely be transcribed, but typically without functional consequence
04
Disease associations
No established roles in diseasePseudogenes in general can sometimes have regulatory or modulatory effects on gene expression, but no direct evidence exists for RNA5SP158 specifically
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