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RNA, 5S ribosomal pseudogene 18 is annotated as a pseudogene related to the 5S ribosomal RNA gene family. While functional 5S rRNA is a ubiquitous component of cytoplasmic ribosomes involved in translation and protein synthesis[1][3][5], pseudogenes like RNA5SP18 are typically non-functional genomic elements that arise from gene duplication or retrotransposition and accumulate mutations that prevent them from encoding a full-length, active RNA or protein. Some pseudogenes produce transcripts which may have regulatory effects—such as interacting with microRNAs or RNA-binding proteins—but most do not have direct biological roles or therapeutic relevance[4][6]. RNA5SP18 is catalogued in gene databases for reference but is not recognized as a functional ribosomal RNA gene, nor as a targetable molecule in drug development. In summary, RNA, 5S ribosomal pseudogene 18 is a non-coding pseudogene of the 5S rRNA family, and is not an established therapeutic target, biomarker, or drug-interacting molecule in current biomedical literature[2][4][5][6].
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