Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 18 (RNA5SP18)

Target
RNA5SP18
Molecular classification
Pseudogene, Non-coding RNA, Other
01

Overview

RNA, 5S ribosomal pseudogene 18 is annotated as a pseudogene related to the 5S ribosomal RNA gene family. While functional 5S rRNA is a ubiquitous component of cytoplasmic ribosomes involved in translation and protein synthesis[1][3][5], pseudogenes like RNA5SP18 are typically non-functional genomic elements that arise from gene duplication or retrotransposition and accumulate mutations that prevent them from encoding a full-length, active RNA or protein. Some pseudogenes produce transcripts which may have regulatory effects—such as interacting with microRNAs or RNA-binding proteins—but most do not have direct biological roles or therapeutic relevance[4][6]. RNA5SP18 is catalogued in gene databases for reference but is not recognized as a functional ribosomal RNA gene, nor as a targetable molecule in drug development. In summary, RNA, 5S ribosomal pseudogene 18 is a non-coding pseudogene of the 5S rRNA family, and is not an established therapeutic target, biomarker, or drug-interacting molecule in current biomedical literature[2][4][5][6].

Other names
RN5S18RNA5SP18RNA, 5S ribosomal 18RNA, 5S ribosomal pseudogene 18
02

Mechanism of action

None

03

Biological functions

Some pseudogenes, when transcribed, can act as regulatory RNAs (e.g., antisense RNA, competing endogenous RNA (ceRNA), or modulate RNA stability by interacting with RNA-binding proteins), but direct experimental evidence for such functions for RNA5SP18 is lacking
04

Disease associations

Other. While some pseudogenes are linked to cancer or regulatory roles, there is no evidence tying RNA5SP18 specifically to any disease

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