RNA, 5S ribosomal pseudogene 198 (RNA5SP198)

RNA, 5S ribosomal pseudogene 198 is a processed rRNA pseudogene, related in sequence to the functional 5S ribosomal RNA gene but does not produce a functional RNA molecule or protein, and does not contribute directly to ribosomal structure or function. Pseudogenes like RNA5SP198 are typically regarded as genomic relics, often generated by the reverse transcription and reintegration of ancestral RNA sequences, and are non-functional remnants marked by mutations and lack of regulatory regions required for transcription[2]. While the functional 5S rRNA molecule is a conserved component of the large ribosomal subunit essential for protein synthesis[1][3], this pseudogene form does not serve those roles. However, global pseudogene expression patterns, including those from rRNA pseudogenes, are being investigated as potential biomarkers and regulators in cancer[4][6], but there is no evidence that RNA5SP198 specifically serves such roles. RNA5SP198 is not a therapeutic target, drug receptor, enzyme, or transporter. Most references to RNA5SP198 in databases are for annotation purposes only, and it is considered non-functional. If you require a canonical 5S ribosomal RNA entry (the actual RNA essential for ribosome function), that would be "5S ribosomal RNA (5S rRNA)" rather than the pseudogene. RNA5SP198 is best classified as a non-coding RNA pseudogene, not a druggable or therapeutic target[2].

Other names

RN5S198RNA5SP198RNA, 5S ribosomal 198