RNA, 5S ribosomal pseudogene 22 (RNA5SP22)

RNA, 5S ribosomal pseudogene 22 (RNA5SP22) is a processed pseudogene that is homologous to the human 5S ribosomal RNA gene but is generally non-functional as a protein- or ribosomal RNA-coding gene[2][4][5]. Processed pseudogenes are formed by reverse transcription of a parental (in this case, 5S rRNA) transcript and reintegration into the genome without introns or regulatory elements, and typically accumulate disabling mutations making them unable to produce functional RNA components of the ribosome[1][3][5]. While most pseudogenes are not actively transcribed or translated, a subset can be transcribed at low levels and may participate in regulatory RNA networks, including acting as microRNA sponges or producing regulatory RNAs, though this has not been shown for RNA5SP22 specifically[3][6][8]. There is no evidence that RNA5SP22 is a therapeutic target, interacts with drugs, or serves as a biomarker or is subject to direct safety or therapeutic interest.\n\nSummary:\nRNA5SP22 is a processed, non-coding pseudogene derived from the 5S ribosomal RNA gene. It is not a therapeutic target, has no known direct biological or disease function, and does not interact with drugs. Its main scientific relevance is in genomic annotation and understanding the evolutionary and regulatory landscape of the human genome[2][4][5].

Other names

RN5S22RNA, 5S ribosomal 22RNA5SP22