Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 23 (RNA5SP23)

Target
RNA5SP23
Molecular classification
Other (pseudogene)
01

Overview

RNA, 5S ribosomal pseudogene 23 (RNA5SP23) is a processed pseudogene related to the 5S ribosomal RNA gene, annotated in the human genome but not believed to produce a functional RNA or protein product[4]. Pseudogenes like RNA5SP23 arise from gene duplication or retrotransposition events and typically accumulated mutations that render them unable to code for active molecules[2]. While some pseudogenes have regulatory effects or are expressed in certain cellular contexts, there is no evidence that RNA5SP23 is a functional therapeutic target, nor is it classified as an enzyme, receptor, transporter, or transcription factor[4][2]. It is best understood as a byproduct of genome evolution. Key points: - RNA5SP23 is a pseudogene and not a druggable or therapeutic target; it does not encode a functional 5S ribosomal RNA or any other protein. - Pseudogenes are a molecular classification separate from active genes and do not participate directly in classical biological functions or pathways[2]. - There are no known drugs, mechanisms of action, or safety concerns associated with RNA5SP23. - Incorrect as a therapeutic target: Since it is a pseudogene and not a gene product with molecular function, there is a fundamental issue if it is being considered as a classical "target"[4][2].

Other names
RN5S23RNA, 5S ribosomal 23RNA5SP23
02

Biological functions

None (as a pseudogene, it does not encode a functional gene product[2][4])
03

Disease associations

Other (expression of pseudogenes can be linked to gene regulatory roles or serve as molecular markers in certain cancers, but there is no established disease role for RNA5SP23 specifically[8])

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