RNA, 5S ribosomal pseudogene 291 (RNA5SP291)

RNA, 5S ribosomal pseudogene 291 (RNA5SP291) is a human pseudogene that belongs to the class of 5S ribosomal RNA (rRNA) pseudogenes[1][2][4]. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they result from gene duplication or retrotransposition but lack the ability to produce functional proteins or RNAs. 5S rRNA pseudogenes, including RNA5SP291, generally do not encode functional ribosomal RNA but may, in some cases, play roles in gene regulation. Such roles can include acting as molecular decoys for microRNAs or generating small interfering RNAs that might regulate their parent gene or others at the RNA level, though this is not uniformly established for all pseudogenes[6]. There is no evidence that RNA5SP291 has a direct biological function, involvement in disease, or status as a therapeutic target[1][2][4]. Summary context: - RNA5SP291 is formally catalogued as a pseudogene in the human genome without known therapeutic or biomarker significance[1][2][4]. - The functional 5S rRNA itself is a key ribosomal structural RNA, but pseudogenes such as RNA5SP291 typically have no direct functional output[3][5][7]. - The broader category of pseudogenes can, in some genetic contexts, regulate gene expression as competitive endogenous RNAs or precursors for small RNAs, but such functions are only documented for selected pseudogenes and are not attributed specifically to RNA5SP291[6].

Other names

RN5S291RNA5SP291RNA, 5S ribosomal 291