RNA, 5S ribosomal pseudogene 304 (RNA5SP304)

RNA, 5S ribosomal pseudogene 304 (abbreviated as RNA5SP304) is classified as a **pseudogene** and is not a protein-coding gene or functional non-coding RNA in the classical sense[1][2]. Pseudogenes are genomic DNA sequences similar to normal genes but typically contain mutations or lack regulatory elements that prevent their expression or result in a non-functional product[2]. The RNA5SP304 gene is related to the **5S ribosomal RNA** family but, as a pseudogene, it does not produce functional 5S rRNA and is not incorporated into ribosomes or involved in protein synthesis[1][2][3][5]. The functional 5S rRNA is a structural component of the large ribosomal subunit, required for ribosome assembly and function[3][5], but the pseudogene version does not contribute to these activities. While some pseudogenes can occasionally exert regulatory effects at the RNA level (e.g., as antisense transcripts or by affecting regulatory networks), there are no specific functional data implicating RNA5SP304 in biological processes or disease states. Pseudogene expression profiles have been studied for their potential as biomarkers in cancer and other diseases[4], but RNA5SP304 itself does not currently have a known disease association or role as a therapeutic target. Thus, it is considered a "non-functional" or "inactive" genetic element for the purposes of drug discovery. Key points: - **RNA5SP304** is a pseudogene and not a protein, enzyme, receptor, transporter, or any classical drug target[1][2]. - It is not a therapeutic target, nor are there any pharmacological agents that act on it. - Its biological and clinical relevance, if any, would be indirect—such as being part of pseudogene expression panels or studied for potential regulatory non-coding effects[2][4]. - The entry is considered **incorrect as a drug target**, as its gene class (pseudogene) is not compatible with conventional target ontologies used in drug development. **Note:** If a structured database is being built to catalog therapeutic targets, RNA5SP304 should be marked as a pseudogene and excluded from lists of actionable biomolecule targets.

Other names

RN5S304RNA, 5S ribosomal 304RNA5SP304