Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 354 (RNA5SP354)

Target
RNA5SP354
Molecular classification
Pseudogene, rRNA pseudogene, Non-coding RNA pseudogene
01

Overview

The RNA, 5S ribosomal pseudogene 354 (RNA5SP354) is classified as a pseudogene corresponding to a defunct or nonfunctional copy of a 5S ribosomal RNA gene, lacking evidence for production of functional RNA or involvement in canonical ribosomal activity. 5S ribosomal RNA is a structural RNA component of the large ribosomal subunit and is critical to ribosome function, but pseudogenes such as RNA5SP354 typically do not produce functional RNA and accumulate mutations that render them transcriptionally or functionally inactive. RNA5SP354 has not been demonstrated to play a role as a therapeutic target, biomarker, or have known interactions with drugs. Its presence is primarily of genomic interest, useful for studies of genome evolution and pseudogene biology, rather than therapeutic or mechanistic research.

Other names
RN5S354RNA, 5S ribosomal 354RNA5SP354
02

Biological functions

Generally lacks biological function; typical of pseudogenes
03

Disease associations

Other (While some pseudogenes may be expressed and could have regulatory or disease roles, there is no evidence for direct involvement of RNA5SP354 in disease)

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