RNA, 5S ribosomal pseudogene 364 (RNA5SP364)

**RNA, 5S ribosomal pseudogene 364 (RNA5SP364)** is annotated as a pseudogene related to the 5S ribosomal RNA (5S rRNA) gene[3]. Pseudogenes are genomic DNA sequences similar to normal genes but typically non-functional due to mutations or lack of regulatory elements necessary for expression[2][3]. RNA5SP364 is classified as a non-coding RNA pseudogene, specifically an rRNA pseudogene, and does not encode a functional product nor participate in canonical ribosome structure or function[2][3]. There is no evidence that RNA5SP364 itself is a therapeutic target, disease-associated gene, biomarker, or involved in drug interactions. While some pseudogenes elsewhere in the genome have been studied for possible regulatory roles or association with disease processes, there is no literature or database evidence to suggest that RNA5SP364 itself has such functional or clinical significance[3][4][6]. **Note:** This entry is "incorrect" as a therapeutic target because RNA5SP364 is not a functional protein, receptor, enzyme, or druggable gene. It is a non-coding, non-functional genomic element without validated biological activity or therapeutic potential[3][2]. The name closely resembles that of true 5S ribosomal RNA; however, functional 5S rRNA (not a pseudogene) is a key part of the ribosome involved in protein synthesis[1][5]. In contrast, RNA5SP364 is a processed pseudogene, not a target[2][3].

Other names

RN5S364RNA, 5S ribosomal 364RNA5SP364