RNA, 5S ribosomal pseudogene 372 (RNA5SP372)

RNA, 5S ribosomal pseudogene 372 (RNA5SP372) is classified as a processed pseudogene derived from the 5S ribosomal RNA gene family, lacking introns and generally arising from reverse transcription of RNA followed by genomic integration[2][6]. Unlike its parent 5S rRNA gene, which serves as a structural and functional component of the large ribosomal subunit involved in protein synthesis[3][5][7], RNA5SP372 does not encode a functional ribosomal RNA and does not have a known biological or pharmacological role[2][6]. Pseudogenes such as RNA5SP372 are ubiquitous in the genome and can sometimes influence gene regulation by acting as competing endogenous RNAs, antisense transcripts, or miRNA decoys, but direct evidence for such activity is gene- and context-specific and not established for this particular pseudogene[4]. RNA5SP372 is catalogued in gene databases for reference, but is not regarded as a therapeutic target, nor does it encode a protein or active RNA product[1][6].

Other names

RN5S372RNA, 5S ribosomal 372RNA5SP372