Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 376 (RNA5SP376)

Target
RNA5SP376
Molecular classification
Pseudogene, rRNA pseudogene, Non-coding RNA
01

Overview

RNA, 5S ribosomal pseudogene 376 (RNA5SP376) is classified as a non-coding RNA pseudogene related to the 5S ribosomal RNA gene family.[3][4] Pseudogenes like RNA5SP376 arise from duplication or retrotransposition events and typically do not encode functional RNA molecules, but may occasionally be transcribed and produce RNA with regulatory functions.[2] These may act as competing endogenous RNAs (ceRNAs) or influence gene regulation by miRNA sponging or lncRNA generation, but there is no evidence for direct involvement in protein synthesis or as targets for therapeutic intervention.[2][6]

Other names
RN5S376RNA5SP376RNA, 5S ribosomal 376
02

Biological functions

May act as a competing endogenous RNA (ceRNA) or miRNA decoyMay be transcribed and influence gene regulation, but does not encode a protein or functional ribosomal RNAPotential to influence epigenetic regulation or generate lncRNAs
03

Disease associations

Other (pseudogenes can play roles in gene regulation and have been sporadically implicated in diseases via ceRNA or regulatory mechanisms, but specific data for RNA5SP376 is lacking)

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