RNA, 5S ribosomal pseudogene 377 (RNA5SP377)

RNA, 5S ribosomal pseudogene 377 (RNA5SP377) is a human processed pseudogene derived from the 5S ribosomal RNA gene family[5]. Unlike the functional 5S ribosomal RNA, which is an essential component of the large ribosomal subunit and necessary for protein synthesis in cells[1][3], pseudogenes such as RNA5SP377 do not produce functional RNA molecules and are generally considered non-coding genetic elements, often resulting from reverse transcription and genomic integration of parental 5S rRNA copies[6]. They lack introns and frequently accumulate sequence changes that prevent them from functioning as true genes[2][6]. There are no current reports linking RNA5SP377 to any disease, regulatory function, or therapeutic targeting strategies. For structured data extraction and target databases, RNA5SP377 should not be considered a functional or druggable target. Its presence in the genome serves mainly as a non-functional copy, and its name might appear in genomic, transcriptomic, or pseudogene catalogs rather than therapeutic contexts.

Other names

RN5S377RNA5SP377RNA, 5S ribosomal 377

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