RNA, 5S ribosomal pseudogene 383 (RNA5SP383)

RNA, 5S ribosomal pseudogene 383 (RNA5SP383) is a non-functional genetic element classified as a processed pseudogene of the 5S ribosomal RNA gene family[1]. Pseudogenes such as RNA5SP383 arise by duplication or retrotransposition events and lack coding potential due to mutations or truncations. Unlike functional 5S rRNA genes—which are integral to the ribosomal large subunit—pseudogenes do not contribute directly to ribosomal biogenesis, protein synthesis, or other canonical cellular pathways[3][5]. While some pseudogenes have emerging regulatory roles in gene expression, particularly in cancer biology as competitive endogenous RNAs or modulators of their parent genes[2][6], there is no functional or disease-related evidence specific to RNA5SP383. It is not documented in clinical, pharmacological, or biomarker contexts and should not be considered a valid therapeutic target. Summary of Key Issues: - RNA5SP383 is a pseudogene, not a protein or enzyme, and not a “target” in the pharmacological or receptor sense[1]. - There is no evidence for its involvement as a therapeutic target or biomarker. - There is no known protein product, receptor, or drug interaction. - Its listing as a target is likely due to a misunderstanding or error regarding its functional status.

Other names

RN5S383RNA5SP383RNA, 5S ribosomal 383