RNA, 5S ribosomal pseudogene 493 (RNA5SP493)

RNA, 5S ribosomal pseudogene 493 (RNA5SP493) is a non-coding RNA gene classified as a processed pseudogene in the human genome, specifically annotated by HGNC as HGNC:43393[2][4]. It shares sequence homology with functional 5S ribosomal RNA genes but has lost the ability to encode functional RNA due to mutations or deletions[6]. While 5S rRNA plays an essential role as a structural RNA component in the ribosome, pseudogenes like RNA5SP493 are generally nonfunctional and do not contribute to ribosome assembly or protein synthesis[1][3]. Some pseudogenes can exert regulatory effects on gene expression via siRNAs, lncRNAs, or by acting as miRNA decoys, but there is no direct evidence or characterization of such roles for RNA5SP493 specifically[6]. This locus is not considered a therapeutic target, lacks known interacting drugs, and has no described utility as a biomarker or role in human disease. Key notes: - This is a pseudogene ("rRNA_pseudogene"), not a functional ribosomal RNA nor a canonical therapeutic target[2][4][6]. - No evidence exists for its protein-coding potential, pharmacological targeting, or direct clinical significance. - The gene is likely included in genomic databases for completeness but does not have a defined physiological or disease-modifying function.

Other names

RN5S493RNA5SP493RNA, 5S ribosomal 493