RNA, 5S ribosomal pseudogene 86 (RNA5SP86)

RNA, 5S ribosomal pseudogene 86 (RNA5SP86) is classified as a *pseudogene* of the 5S ribosomal RNA gene family[2][4]. Located at chromosome 2p24.1, it does not encode a functional RNA or protein product, as pseudogenes typically arise from duplication or retrotransposition events and accumulate disabling mutations[4]. The functional counterpart, 5S ribosomal RNA, is a ~120-nucleotide structural RNA essential for large ribosomal subunit assembly and protein synthesis in living cells[3][1]. However, pseudogenes like RNA5SP86 are *not incorporated into ribosomes* and do not produce functional ribosomal components[2][4]. While some pseudogenes have been shown to regulate their parent genes or act as non-coding RNAs with regulatory functions[8], there is currently no reported evidence that RNA5SP86 has such activity or is relevant for human disease or drug interactions. Therefore, it is **not considered a therapeutic target**, and listing it as a drug target would be incorrect. **Notes on correctness:** - RNA5SP86 is frequently mistaken for a functional RNA or mis-annotated as a true target due to its name, but it is a **pseudogene**[2][4]. - If your aim is to identify drug targets or functionally relevant molecules, **RNA5SP86 should not be included**. - It has no recognized direct molecular, cellular, or disease function relevant to therapeutics or diagnostics. **Summary:** RNA, 5S ribosomal pseudogene 86 (RNA5SP86) is a non-functional genomic element and not a valid molecular target; any attempt to treat it as such is incorrect[2][4].

Other names

RN5S86RNA5SP86RNA, 5S ribosomal 86