RNA, 5S ribosomal pseudogene 89 (RNA5SP89)

RNA, 5S ribosomal pseudogene 89 (RNA5SP89) is a human pseudogene that shares sequence similarity with the gene encoding 5S ribosomal RNA[2][4][6]. 5S ribosomal RNA is a highly conserved, small RNA component of the large ribosomal subunit, essential for ribosome stability and protein synthesis[1][3][5][7][9]. However, RNA5SP89 itself is classified as a pseudogene, meaning it does **not produce a functional ribosomal RNA** and is not integrated into active ribosomes[2][4][6]. Pseudogenes typically arise from gene duplication or retrotransposition and subsequently lose their original function due to mutations[10]. Most pseudogenes are considered nonfunctional, although some can have regulatory roles (for example, by acting as RNA decoys or sources of small RNAs), but there is no evidence that RNA5SP89 fulfills such a role[2][4][10]. There is no therapeutic relevance, no known disease mechanism, and no known drug or biomarker associated with this specific pseudogene. Key takeaways: - **RNA5SP89 is a noncoding pseudogene, not an active molecular target.** - **It should not be considered a druggable or therapeutic target.** - **It is not linked to any specific biological process or disease as a functional molecule.**

Other names

RN5S89RNA, 5S ribosomal 89RNA5SP89