RNA, 7SK small nuclear pseudogene 130 (RN7SKP130)

RN7SK pseudogene 130 (RN7SKP130) is classified as a pseudogene, meaning it is a non-functional segment of DNA related to the functional RN7SK gene, which encodes the 7SK small nuclear RNA. The canonical RN7SK gene is a highly conserved, non-coding RNA transcribed by RNA polymerase III that forms a ribonucleoprotein complex (7SK snRNP) and serves as a global regulator of RNA polymerase II transcription elongation by sequestering positive transcription elongation factor b (P-TEFb)[4][6]. The RN7SK pseudogenes, including RN7SKP130, arise through retrotransposition or duplication events and lack evidence for functional RNA or protein products[3]. Pseudogenes like RN7SKP130 are not known to be involved in cellular processes, disease mechanisms, or as targets for therapeutic drugs. Structured and authoritative gene resources do not associate RN7SK pseudogene 130 with any protein, regulatory function, disease process, or therapeutic class[5]. If information about RN7SKP130 is sought as a "receptor", "enzyme", or regulatory target, this is "incorrect"—it is a pseudogene and does not fulfill such roles.

Other names

RN7SK pseudogene 130RN7SKP130RNA, 7SK small nuclear pseudogene 130