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RNA, 7SK small nuclear pseudogene 148 (RN7SKP148) is a pseudogene related to the functional 7SK snRNA gene. The canonical 7SK snRNA regulates transcription elongation in human cells by sequestering positive transcription elongation factor b (P-TEFb) in a ribonucleoprotein complex, serving as an RNA scaffold essential for gene expression regulation[1][2][5]. However, RN7SKP148 itself is considered a non-coding RNA pseudogene, meaning it is an unprocessed genomic remnant with no established function or protein coding potential, and is not a recognized therapeutic or biological target. Pseudogenes like RN7SKP148 are generally presumed to be non-expressed and not involved in regulation, disease, or drug action[3][4]. If you are seeking a functional therapeutic target, you should refer to "RNA, 7SK small nuclear RNA" (RN7SK), not RN7SKP148[2][5].
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