RNA, 7SK small nuclear pseudogene 88 (RN7SKP88)

RN7SK pseudogene 88 (RN7SKP88) is a genomic DNA sequence that resembles the RN7SK small nuclear RNA gene but is classified as a pseudogene, meaning it is generally non-functional and does not encode a biologically active RNA or protein product. Pseudogenes arise through duplication or retrotransposition and typically lack regulatory elements required for expression. RN7SKP88 does not participate in the molecular functions attributed to RN7SK, such as regulation of transcriptional elongation, control of cellular differentiation, or involvement in human disease. Functional RN7SK, in contrast, is a critical regulatory non-coding RNA that modulates transcription by sequestering and controlling positive transcription elongation factor b (P-TEFb), and is important in cellular processes like cell cycle regulation, differentiation, and immune response[1][2][3][4][5]. Clarification: Results and scientific literature frequently discuss RN7SK (active small nuclear RNA), not RN7SKP88 (pseudogene). Therefore, RN7SKP88 should not be considered a molecular target or receptor in therapeutic contexts. If your interest lies in the functional small nuclear RNA, RN7SK would be the correct molecule to investigate.

Other names

RN7SKP88RNA, 7SK small nuclear pseudogene 88