RNA, 7SL, cytoplasmic 125, pseudogene (RN7SL125P)

RNA, 7SL, cytoplasmic 125, pseudogene (RN7SL125P) is a **pseudogene** derived from the 7SL RNA gene, which codes for the RNA component of the signal recognition particle (SRP)[4][7]. The canonical 7SL RNA plays a central role in targeting newly synthesized secretory and membrane proteins to the endoplasmic reticulum by acting as a scaffold in the SRP complex[3][5][6]. However, **7SL RNA pseudogenes**, such as RN7SL125P, are generally non-functional genetic elements—their sequences resemble the 7SL RNA gene but accumulate mutations, truncations, and are not typically transcribed into functional RNA or protein[1][4][7]. They arose through the process of reverse transcription and random insertion into the genome, explaining their abundance and sequence variability in humans[1][6][7]. RN7SL125P is not considered a therapeutic target, does not have a known role in normal physiology or disease, and has no known drug or biomarker associations[4][7]. **Notes:** - RN7SL125P is a pseudogene and not a functional gene or a protein/molecular target. - 7SL RNA has functional importance, but its pseudogenes (including RN7SL125P) do not have established biological functions or disease roles in current scientific literature[1][3][4][6][7]. - There is nothing to indicate it is a drug target or biomarker; if the intended target is the functional 7SL RNA or the SRP complex, a different entry should be used.

Other names

RN7SL125P