RNA, 7SL, cytoplasmic 148, pseudogene (RN7SL148P)

**RNA, 7SL, cytoplasmic 148, pseudogene (RN7SL148P)** is a member of a large family of human pseudogenes that are homologous to the 7SL RNA gene. The parental 7SL RNA, also called signal recognition particle RNA, is an essential component of the signal recognition particle complex, mediating the co-translational targeting of proteins to the endoplasmic reticulum[3][5]. However, **RN7SL148P is a pseudogene**—a nonfunctional genomic segment that derives from the original 7SL RNA gene, typically through retrotransposition and subsequent loss of function[1][6][7]. Such pseudogenes are not translated into functional RNAs or proteins and do not exert known biological activity or therapeutic relevance. Pseudogenes like RN7SL148P are generally not considered therapeutic targets; their principal significance is in genomics studies or possibly as regulatory RNAs in rare cases, but no such function is documented for RN7SL148P specifically[1][7].\n\n**Key clarifications:**\n- RN7SL148P is not a functional protein, receptor, enzyme, or any other recognized therapeutic target class[1][7].\n- It is not associated with any diseases, biological functions, or drug interactions currently recognized in the scientific literature[1][7].\n- As a **pseudogene**, it is typically considered a genomic artifact rather than an active biological entity[6][7].\n- The entry is flagged as **incorrect as a drug target** due to its pseudogene status.\n\n**Summary:** \nRN7SL148P is a non-coding RNA pseudogene related to the 7SL RNA gene; it does not encode a functional biological molecule and is not a therapeutic target[1][7].

Other names

RN7SL148P7SL RNA pseudogene 148RNA, 7SL, cytoplasmic 148, pseudogene