Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 149, pseudogene (RN7SL149P)

Target
RN7SL149P
Molecular classification
Non-coding RNA, Pseudogene, Miscellaneous RNA
01

Overview

RNA, 7SL, cytoplasmic 149, pseudogene (RN7SL149P) is a human pseudogene belonging to the family of 7SL RNA-derived sequences. The 7SL RNA is a central non-coding RNA component of the signal recognition particle (SRP), which facilitates proper targeting of proteins to the endoplasmic reticulum. However, RN7SL149P itself is a processed, nonfunctional pseudogene copy of 7SL RNA and is not known to be transcribed into functional RNA or protein. Hundreds of similar 7SL RNA pseudogenes exist in the human genome, almost all arising from reverse transcription and genomic insertion of RNA intermediates, often with truncations and mutations rendering them nonfunctional. RN7SL149P, according to current evidence, does not perform any biological or therapeutic function and is not a drug target.

Other names
RN7SL149P7SL pseudogene 1497SL RNA pseudogene 149
02

Mechanism of action

None

03

Biological functions

None (no known direct biological function; nonfunctional pseudogene)
04

Disease associations

Other (no reported direct disease association; noncoding pseudogenes like RN7SL149P can sometimes indirectly affect gene expression through regulatory roles, but there is no specific evidence for this gene)

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