RNA, 7SL, cytoplasmic 177, pseudogene (RN7SL177P)

RN7SL177P is a pseudogene located in the human genome, representing a truncated or mutated copy of the gene encoding 7SL RNA, a non-coding RNA component of the signal recognition particle (SRP)[1][7]. The **7SL RNA** serves as a scaffold within the SRP, which guides the cotranslational insertion of secretory proteins into the endoplasmic reticulum[5][3]. Unlike the genuine RN7SL1 gene (7SL RNA), RN7SL177P does not produce a functional RNA, nor does it participate directly in protein targeting or cellular signaling[1][7]. Most 7SL pseudogenes, including RN7SL177P, arose via reverse transcription and DNA integration and are not expressed or functional in normal cells[7]. There are currently no established disease roles, clinical relevance, or therapeutic implications for RN7SL177P. If you need information about the actual **functional 7SL RNA (RN7SL1)**, which plays an essential role in SRP-mediated protein targeting and is implicated in certain cancer pathways[5][3], refer to RN7SL1, not RN7SL pseudogenes.

Other names

RN7SL177P7SL RNA pseudogene 177