RNA, 7SL, cytoplasmic 178, pseudogene (RN7SL178P)

**RN7SL178P** is a pseudogene derived from sequences related to **7SL RNA**, the central RNA component of the signal recognition particle (SRP)[2][4]. The SRP is essential for cotranslational targeting of secretory proteins to the endoplasmic reticulum in eukaryotic cells[3][1][5]. The human genome contains hundreds of 7SL RNA-like sequences, most of which are pseudogenes formed by reverse transcription and genomic insertion of truncated or mutated 7SL RNA transcripts. These pseudogenes do not produce functional RNA and do not participate in the SRP role[4]. Unlike functional RNAs such as **RN7SL1**, which are essential for protein targeting and have been implicated in disease contexts (cancer, neuroinflammation, antiviral defense)[1][5], **RN7SL178P** is structurally related but classified as a **pseudogene**, meaning it lacks biological function, is not a therapeutic target, and has no known role in pathogenesis or pharmacology[2][4]. These pseudogenes are mainly used to study genomic evolution, transposable elements (Alu family origins)[3], and molecular taxonomy.

Other names

RN7SL178P7SL pseudogeneRNA, 7SL, cytoplasmic 178, pseudogene

None reported