RNA, 7SL, cytoplasmic 209, pseudogene (RN7SL209P)

RN7SL209P is a human pseudogene closely related to the canonical 7SL RNA gene. The canonical 7SL RNA is integral to the Signal Recognition Particle (SRP), a ribonucleoprotein involved in cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum in eukaryotic cells[1][5]. RN7SL209P, as a pseudogene, is a noncoding RNA sequence that has lost its original function and does not encode a functional RNA or protein product. 7SL RNA pseudogenes typically arise by reverse transcription of 7SL RNA followed by insertion into genomic DNA, often showing truncations at either the 5’ or 3’ ends[3][8]. While some pseudogenes in the human genome may play regulatory roles—such as serving as competitive endogenous RNAs (ceRNAs), miRNA sponges, or having tissue-specific expression—there is no direct evidence that RN7SL209P shows such activity[2][4][6][9]. The majority of 7SL-like sequences in human DNA are pseudogenes, and only a small number actually encode the functional SRP RNA[8][9]. RN7SL209P is not considered a therapeutic target, receptor, or enzyme, and is not associated with human disease or pharmacological intervention.

Other names

RN7SL209PRNA, 7SL, cytoplasmic 209, pseudogene7SL pseudogene

Not applicable; not a canonical drug target