RNA, 7SL, cytoplasmic 220, pseudogene (RN7SL220P)

RNA, 7SL, cytoplasmic 220, pseudogene (RN7SL220P) is classified as a **pseudogene** derived from the 7SL RNA gene family, which encodes the RNA core of the signal recognition particle (SRP), a ribonucleoprotein complex essential for targeting newly synthesized proteins to the endoplasmic reticulum[6][2][3][1][5]. As a pseudogene, RN7SL220P is a genomic locus that resembles the functional 7SL RNA gene but harbors mutations or structural changes that render it non-functional in classical SRP assembly and protein targeting. While some pseudogenes can be transcribed and potentially play *regulatory roles* (such as acting as microRNA decoys or sources of non-coding RNAs that modulate parental gene expression), there is currently no specific evidence that RN7SL220P itself has direct biological function or disease association. It is not a recognized therapeutic target, receptor, enzyme, transporter, or transcription factor. Its presence largely reflects the high evolutionary mobility and duplication history of the 7SL RNA family in the genome, which is also the source of human Alu repeats[1][5]. Pseudogenes like RN7SL220P are primarily used as markers in evolutionary and functional genomics research and are not directly targeted by drugs or therapeutics[6][2][4].

Other names

RN7SL220P7SL RNA pseudogeneRNA, 7SL, cytoplasmic 220, pseudogene