RNA, 7SL, cytoplasmic 292, pseudogene (RN7SL292P)

RNA, 7SL, cytoplasmic 292, pseudogene (RN7SL292P) is a human **pseudogene** that is part of a large family of non-coding RNAs derived from the 7SL RNA gene, which encodes the RNA component of the **signal recognition particle (SRP)** complex[1][3][6]. The functional 7SL RNA is essential for directing newly synthesized proteins to the endoplasmic reticulum by pausing translation and targeting the ribosome-protein complex to the membrane, but RN7SL292P itself does **not encode any functional protein or RNA product** and is considered a "dead" genetic element[5][7][8]. Instead, like many pseudogenes, it likely arose from a process in which a functional RNA gene was reverse transcribed and reinserted into the genome, resulting in a sequence that no longer produces a functional product[7][8]. While some 7SL pseudogenes in general have been implicated in gene regulation or disease mechanisms as competitive endogenous RNAs, there is **no current evidence of any biological or disease-related role for RN7SL292P specifically**[4]. RN7SL292P is not a drug target, is not associated with any disease, and has no known impact on patient selection, therapy, or safety.

Other names

RN7SL292PRNA, 7SL, cytoplasmic 292, pseudogene