Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 332, pseudogene (RN7SL332P)

Target
RN7SL332P
Molecular classification
Other (Pseudogene, Non-coding RNA, 7SL RNA pseudogene)
01

Overview

**RN7SL332P** is a human pseudogene corresponding to the 7SL RNA, which is the RNA component of the signal recognition particle (SRP), but as a pseudogene it does not produce a functional product[1][3]. 7SL RNA is essential for the SRP complex, which mediates the targeting of secretory proteins to the endoplasmic reticulum, but pseudogenes like RN7SL332P are typically non-functional and are derived from the reverse transcription and integration of 7SL RNA sequences back into the genome, often as truncated, non-expressed copies[1][3]. While some pseudogenes can be transcribed and exert regulatory effects—such as acting as microRNA decoys (competing endogenous RNAs)—there is no evidence that RN7SL332P is functionally expressed, nor is it a recognized therapeutic target or clinically relevant biomarker[1][2][4]. Most pseudogenes, including RN7SL332P, are considered genomic fossils; however, general research into pseudogene biology suggests a minority may be involved in gene regulation under specific biological contexts[2][4]. **Key points supporting “is_incorrect: true”**: - **RN7SL332P is a pseudogene, not a functional receptor, enzyme, transporter, or any classical drug target**[1][2][3]. - Pseudogenes are not typically referred to as receptors or used as direct therapeutic targets[1][3][4]. - There is no evidence RN7SL332P is involved in disease, relates to a known mechanism of action, or interacts with any drugs. **In summary:** RN7SL332P represents a non-functional, non-coding RNA pseudogene derived from the 7SL RNA component of the SRP, with no direct biological function, druggability, or disease relevance as an individual target[1][3][4].

Other names
RN7SL332PRNA, 7SL, cytoplasmic 332, pseudogene
02

Mechanism of action

None (not a drug target)

03

Biological functions

None (as a pseudogene)may act as a competing endogenous RNA (ceRNA) or miRNA sponge by analogy with some expressed pseudogenesnot directly involved in canonical cell signaling or enzymatic functions
04

Disease associations

Other (no direct evidence for this specific pseudogene; however, the functional 7SL RNA has been implicated in cancer and cellular stress responses, and some pseudogenes may play a regulatory role in disease by altering parental gene expression)

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