RNA, 7SL, cytoplasmic 362, pseudogene (RN7SL362P)

RN7SL362P is a pseudogene derived from the 7SL RNA component of the signal recognition particle. The 7SL RNA is a crucial component of the signal recognition particle (SRP) ribonucleoprotein complex, which plays essential roles in protein targeting to the endoplasmic reticulum, translation regulation, and cellular stress responses[3][4][5][6]. Human genomes contain several hundred 7SL RNA-like sequences, with only about four representing functional genes and the majority being pseudogenes that appear to result from reverse transcription of 7SL RNA back into genomic DNA[3][4]. These 7SL pseudogenes display diverse structures and are typically truncated copies of the parent 7SL RNA, with truncations occurring at various sites including the 5' end, 3' end, or both ends[3][4]. While the parent 7SL RNA has multiple cellular functions including roles in SRP assembly, protein translocation, translation control, and has been implicated in viral processes such as HIV-1 packaging, pseudogenes like RN7SL362P generally lack these functional capabilities[5]. Some pseudogenes may be transcribed and could potentially influence the expression of their parent genes through competitive endogenous RNA mechanisms, but the specific functional significance of RN7SL362P remains to be determined[2].

Other names

7SL RNA pseudogeneSignal recognition particle RNA pseudogene

Not applicable for pseudogenes.