Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 366, pseudogene (RN7SL366P)

Target
RN7SL366P
Molecular classification
Pseudogene, Non-coding RNA, Other
01

Overview

RNA, 7SL, cytoplasmic 366, pseudogene (RN7SL366P) is one of hundreds of 7SL RNA-derived pseudogenes widely dispersed in the human genome. Pseudogenes of 7SL RNA arise via molecular events such as reverse transcription from mature SRP RNA and insertion into DNA. These sequences are generally truncated and non-functional, lacking the ability to code for proteins or contribute to canonical SRP complex function. While the parental 7SL RNA has an essential role in protein translocation as part of the signal recognition particle complex, RN7SL366P and related pseudogenes do not; the vast majority are considered genomic 'fossils'. Pseudogenes may occasionally undergo transcription and play a role as non-coding RNAs, although there is no evidence that RN7SL366P itself is functionally relevant. RN7SL366P is not a functional receptor, transporter, or enzyme, nor is it recognized as a direct disease risk locus or drug target. It is located at cytogenetic band 6q26 in the human genome.

Other names
RN7SL366PRNA, 7SL, cytoplasmic 366, pseudogenemisc RNA
02

Mechanism of action

Not applicable (no known mechanisms or drug actions relevant to this pseudogene)

03

Biological functions

If transcribed, pseudogenes like RN7SL366P may act as non-coding RNAs.Some pseudogenes (not specifically RN7SL366P) have been proposed to function as miRNA sponges or epigenetic regulators, but there is no specific evidence for RN7SL366P.Other
04

Disease associations

Other (No documented direct association with any disease)
05

Safety considerations

None known. Not a therapeutic or diagnostic target; thus, no safety concerns are documented
06

Interacting drugs

None known. No drugs are known to target this pseudogene or its transcript directly
07

Biomarkers

None known. Not used as a biomarker for patient selection or efficacy monitoring

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