Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 383, pseudogene (RN7SL383P)

Target
RN7SL383P
Molecular classification
Other, Pseudogene, Non-coding RNA-derived pseudogene
01

Overview

RN7SL383P is a human genomic pseudogene, part of a large family derived from 7SL RNA, the essential non-coding RNA component of the signal recognition particle (SRP)[1][5][7]. 7SL RNA pseudogenes are diverse, often truncated, and result from the reverse transcription of 7SL RNA and reintegration into the genome. Unlike functional 7SL RNA, which is critical for directing proteins to membranes during translation, 7SL RNA pseudogenes (such as RN7SL383P) are typically not transcribed into functional RNA or protein and lack biological activity[1][5][7]. Their presence in the genome is thought to reflect historical gene duplications and retrotransposition events, but they do not contribute to cellular function or disease and are not drug targets[1][7]. The parent molecule, 7SL RNA, is involved in co-translational protein translocation as part of SRP, but RN7SL383P does not participate in this pathway[6]. There is no misspelling, though it represents a molecule type (pseudogene) that is not a canonical drug target, receptor, enzyme, or transporter. Most research databases and gene resources define RN7SL383P as a "pseudogene" with no known or predicted function[1]. Summary: RN7SL383P is correctly named as a pseudogene, not a receptor, enzyme, or drug target. It is biologically inert, has no disease association, no therapeutically relevant interactions, and should not be considered a therapeutic target.

Other names
RN7SL383PRNA, 7SL, cytoplasmic 383, pseudogene

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